Plos one login | create account | feedback browse rss search search advanced search home browse articles by publication date/subject collections about journal information editorial board section editors advisory board statistical advisors article-level metrics open-access license contact us for readers guidelines for notes, comments, and corrections guidelines for rating help using this site journal club archives media downloads site map for authors and reviewers publication criteria editorial policies manuscript guidelines figure and table guidelines supporting information guidelines submitting a manuscript reviewer guidelines thanking all peer reviewers plos. viagra for sale buy cheap viagra viagra wholesale where is the cheapest place to buy viagra order cheap viagra at the best prices viagra without a doctor prescription generic viagra online cheap viagra generic viagra online buy generic viagra Org open access join plos plos blogs plos store plos currents stay connected hubs biodiversity clinical trials journals plos biology plos medicine plos computational biology plos genetics plos pathogens plos one plos neglected tropical diseases download: pdf | citation | xml print article ezreprint new & improved! Metrics info more related content related subject categories computational biology , computer science , genetics and genomics , mental health , neurological disorders , neuroscience related articles on the web google scholar pubmed more share this article info email this article plos open access research article disc1 and huntington's disease – overlapping pathways of vulnerability to neurological disorder? We re-annotated the interacting partners of the neuronal scaffold protein disc1 using a knowledge-based approach that incorporated recent protein interaction data and published literature to. This revealed two highly connected networks. These networks feature cellular function and maintenance, and cell signaling. Of potentially greatest interest was the novel finding of a high degree of connectivity between the disc1 scaffold protein, linked to psychiatric illness, and huntingtin, the protein which is mutated in huntington's disease. The potential link between disc1, huntingtin and their interacting partners may open new areas of research into the effects of pathway dysregulation in severe neurological disorders. Article metrics related content comments: 0 to add a note, highlight some text. Hide notes make a general comment jump to ruth boxall , david j. Porteous , pippa a. Thomson.

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